Buffalo Bills In Depth Schedule
Season: 2025-2026
| Week | Time & Day | Opponent | Opponent Head Coach | Opponent Quarterback | Stadium Type | Playing Surface |
|---|---|---|---|---|---|---|
| 1 | 8:20pm Sunday | vs BAL | John Harbaugh | Lamar Jackson | Outdoor | Artificial |
| 2 | 1:00pm Sunday | at NYJ | Aaron Glenn | Justin Fields | Outdoor | Artificial |
| 3 | 8:15pm Thursday | vs MIA | Mike McDaniel | Tua Tagovailoa | Outdoor | Artificial |
| 4 | 1:00pm Sunday | vs NO | Kellen Moore | Tyler Shough | Outdoor | Artificial |
| 5 | 8:20pm Sunday | vs NE | Mike Vrabel | Drake Maye | Outdoor | Artificial |
| 6 | 7:15pm Monday | at ATL | Raheem Morris | Michael Penix Jr. | RetractableDome | Artificial |
| 7 | vs BYE | Outdoor | Artificial | |||
| 8 | 1:00pm Sunday | at CAR | Dave Canales | Bryce Young | Outdoor | Artificial |
| 9 | 4:25pm Sunday | vs KC | Andy Reid | Patrick Mahomes | Outdoor | Artificial |
| 10 | 1:00pm Sunday | at MIA | Mike McDaniel | Tua Tagovailoa | Outdoor | Grass |
| 11 | 1:00pm Sunday | vs TB | Todd Bowles | Baker Mayfield | Outdoor | Artificial |
| 12 | 8:15pm Thursday | at HOU | DeMeco Ryans | C.J. Stroud | RetractableDome | Artificial |
| 13 | 4:25pm Sunday | at PIT | Mike Tomlin | Aaron Rodgers | Outdoor | Grass |
| 14 | 4:25pm Sunday | vs CIN | Zac Taylor | pending | Outdoor | Artificial |
| 15 | 1:00pm Sunday | at NE | Mike Vrabel | Drake Maye | Outdoor | Artificial |
| 16 | 1:00pm Sunday | at CLE | Kevin Stefanski | Dillon Gabriel | Outdoor | Grass |
| 17 | 4:25pm Sunday | vs PHI | Nick Sirianni | Jalen Hurts | Outdoor | Artificial |
| 18 | 12:00am Saturday | vs NYJ | Aaron Glenn | Justin Fields | Outdoor | Artificial |