San Francisco 49ers In Depth Schedule
Season: 2025-2026
| Week | Time & Day | Opponent | Opp. Head Coach | Opp. Quarterback | Stadium Type | Playing Surface |
|---|---|---|---|---|---|---|
| 1 |
4:05pm
Sunday
|
at SEA | Mike Macdonald | Sam Darnold | Outdoor | Artificial |
| 2 |
1:00pm
Sunday
|
at NO | Kellen Moore | Tyler Shough | Dome | Artificial |
| 3 |
4:25pm
Sunday
|
vs ARI | None | Kyler Murray | Outdoor | Grass |
| 4 |
4:05pm
Sunday
|
vs JAX | Liam Coen | Trevor Lawrence | Outdoor | Grass |
| 5 |
8:15pm
Thursday
|
at LAR | Sean McVay | Matthew Stafford | Dome | Artificial |
| 6 |
4:25pm
Sunday
|
at TB | Todd Bowles | Baker Mayfield | Outdoor | Grass |
| 7 |
8:20pm
Sunday
|
vs ATL | Kevin Stefanski | Michael Penix Jr. | Outdoor | Grass |
| 8 |
1:00pm
Sunday
|
at HOU | DeMeco Ryans | C.J. Stroud | RetractableDome | Artificial |
| 9 |
1:00pm
Sunday
|
at NYG | John Harbaugh | Jaxson Dart | Outdoor | Artificial |
| 10 |
4:25pm
Sunday
|
vs LAR | Sean McVay | Matthew Stafford | Outdoor | Grass |
| 11 |
4:05pm
Sunday
|
at ARI | None | Kyler Murray | RetractableDome | Grass |
| 12 |
8:15pm
Monday
|
vs CAR | Dave Canales | Bryce Young | Outdoor | Grass |
| 13 |
1:00pm
Sunday
|
at CLE | None | Shedeur Sanders | Outdoor | Grass |
| 14 | vs BYE | Outdoor | Grass | |||
| 15 |
4:25pm
Sunday
|
vs TEN | Robert Saleh | Cameron Ward | Outdoor | Grass |
| 16 |
8:15pm
Monday
|
at IND | Shane Steichen | Daniel Jones | RetractableDome | Artificial |
| 17 |
8:20pm
Sunday
|
vs CHI | Ben Johnson | Caleb Williams | Outdoor | Grass |
| 18 |
8:00pm
Saturday
|
vs SEA | Mike Macdonald | Sam Darnold | Outdoor | Grass |
vs
Home Game
at
Away Game